22 So all bore witness to Him, and marveled at the gracious words which proceeded out of His mouth. And they said, “Is this not Joseph’s son?” 23 He said to them, “You will surely say this proverb to Me, ‘Physician, heal yourself! Whatever we have heard done in Capernaum, do also here in Your country.’ ” 24 Then He said, “Assuredly, I say to you, no prophet is accepted in his own country. 25 But I tell you truly, many widows were in Israel in the days of Elijah, when the heaven was shut up three years and six months, and there was a great famine throughout all the land; 26 but to none of them was Elijah sent except to Zarephath, in the region of Sidon, to a woman who was a widow. 27 And many lepers were in Israel in the time of Elisha the prophet, and none of them was cleansed except Naaman the Syrian.” 28 So all those in the synagogue, when they heard these things, were filled with wrath, 29 and rose up and thrust Him out of the city; and they led Him to the brow of the hill on which their city was built, that they might throw Him down over the cliff. 30 Then passing through the midst of them, He went His way.
Cyril of Alexandria said in his Commentary on Luke:
“Since they did not understand Christ who had been anointed and sent by God, who was the Author of such wonderful works, they returned to their usual ways and said foolish and useless things about him. They wondered at the words of grace that he spoke. Yet they treated these words as worthless. They said, ‘Isn’t this Joseph’s son?’ But how does this diminish the glory of the Worker of the miracles? What prevents him from being both venerated and admired, even had he been, as was supposed, Joseph’s son? Don’t you see the miracles? Satan is fallen, the herds of devils are vanquished, and multitudes are set free from various kinds of sicknesses. You praise the grace that was present in his teachings. Do you, then, in Jewish fashion, think lightly of him, because you thought Joseph was his father? How absurd! Truly it is said about them, ‘See! They are a foolish people. They are without understanding! They have eyes and don’t see, ears, and do not hear.'”
St. John Chrysostom in his Homily XLVIII on Matthew VIII said:
“But mark you, I pray, the Master’s gentleness, how He does not revile them, but with great mildness says, ‘A prophet is not without honor save in his own country.’ Neither did He stop here, but added, ‘And in his own house.’ To me it appears that He made this addition with covert reference to His very own brethren. But in Luke He also gives examples of this, saying that neither did Elias come unto his own, but to the stranger widow, neither was any other leper healed by Eliseus, but the stranger Naaman, and Israelites neither received benefit, nor conferred benefit, but the foreigners did. And these things He says, signifying in every instance their evil disposition, and that in His case nothing new is taking place.”